Iran (IMNA) - Dr. Mohammad Reza Nazer, speaking to IMNA News Agency, clarified that LPR occurs when gastric acid refluxes past the upper esophageal sphincter (UES), reaching the larynx (voice box) and pharynx (throat). “This typically happens when the upper esophageal sphincter fails to function properly, allowing acid to travel higher than usual,” he explained.
He underlined that the mechanisms and symptoms of LPR differ significantly from those of classic heartburn or GERD. “While both conditions result from dysfunction of the esophageal sphincters, heartburn is caused by a defect in the lower esophageal sphincter (LES), leading to acid irritation in the chest area. In contrast, LPR primarily affects the throat and larynx, causing localized symptoms,” Dr. Nazer said.
Unlike GERD, which commonly presents with burning discomfort in the chest, LPR often manifests without heartburn —a reason it is sometimes called ‘silent reflux.’ Patients may not experience the classic digestive symptoms but still suffer from significant irritation in the upper airway.
According to Dr. Nazer, common symptoms of LPR include chronic throat clearing, persistent throat irritation, chronic cough, hoarseness, excessive throat mucus, dysphagia (difficulty swallowing), and the sensation of a lump in the throat. Other associated signs may include regurgitation of food, postnasal drip, weak or strained voice, laryngeal spasms, airway obstruction, and wheezing.
“The reflux of gastric contents into the larynx, even in small amounts, can be highly irritating and lead to prolonged inflammation of the vocal folds and upper respiratory tract,” Dr. Nazer added. “Since many individuals with LPR do not exhibit typical heartburn symptoms, diagnosis often requires careful clinical evaluation and, in some cases, specialized laryngoscopic examination.”
He concluded by stressing the importance of early diagnosis and appropriate management to prevent chronic vocal strain and airway complications.
Original: imna.ir/x9PWS
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